出国体检人员中可疑氯胺酮阳性病例确证分析

    曹洁1，郑可芳2，黄金宝1，肖武1，张绍雨2，高博1，刘依德1，魏春华1，柯秋璇1

    1.福建国际旅行卫生保健中心国家毒品检测重点实验室，福建 福州350001；2.福建警察学院

    摘要：目的 建立一种快速、灵敏的方法用于氯胺酮初筛为阳性后的确证。方法采用传统的液-液萃取法进行人体尿液样品前处理，并结合单四极杆气相色谱质谱联用法（GC/MS）对样品进行确证分析。结果该氯胺酮初筛阳性尿样在确证分析中未检出氯胺酮。被检尿样的GC/MS谱图中未见明显的氯胺酮色谱峰；而经质谱定性后发现谱图中有较高的麻黄素色谱峰。结论本研究建立的GC/MS分析方法对于毒品确证十分准确、有效，可推广应用于其它毒品初筛为阳性的进一步确证实验中。

    关键词：氯胺酮；毒品；确证；单四极杆气相色谱质谱联用法

    中图分类号：R185　文献标识码：B

    Analysis of suspected case with ketaminepositive among exit

    personel using drug affirming testing

    CAO Jie*, ZHENG Ke-fang, HUANG Jin-bao, XIAOWu, ZHANG Shao-yu, GAO Bo,

    LIU Yi-de, WEI Chun-hua, KE Qiu-xuan

    *State Key Laboratory of Drug Detection,Fujian International Travel Healthcare Center, Fuzhou, Fujian350001, China

    Abstract:   Objective  To establish a fast, sensitive affirming testing method todetermine the result of ketamine in elementary drug testing. Methods   Drug affirming testing was done usingtraditional liquid-liquid extraction as sample pretreatment andcombining gas chromatograph-mass spectrometer (GC/MS)methods.   Results   The ketamine was notdetected in drug affirming testing. There was no obvious ketaminepeak in the chromatogram GC/MS methods. However the ephedrine peakcan be observed distinctly in the chromatogram. Conclusion   The new established GC/MS method is veryexact and effective for ketamine affirming, so this method can beapplied to other drug affirming testing.

    Key words:   Ketamine； Drug；Affirming； GC/MS

    《中国国境卫生检疫杂志》