梅毒的分子流行病学研究进展

    周冬根1，孙大为1，张2，张升2，卢培恩2，翟敏2

    1.宁波国际旅行卫生保健中心，浙江 宁波 315012；2.宁波出入境检验检疫局

    摘要：目的近年来，欧美等发达国家梅毒的发病率呈上升趋势，同时梅毒在许多发展中国家高度流行，已经成为一个重要的公共卫生问题。先进的分子流行病学方法也越来越多的应用于梅毒的研究。本文介绍近年来关于梅毒螺旋体的进化变异特征及时间、地域及人群分布特点等分子流行病学方面的研究进展，以便为国境口岸积极有效的防控梅毒提供理论依据。

    关键词：梅毒螺旋体；分子流行病学；分布；防控

    中图分类号：R759.1　文献标识码：B

    Research progress of molecular epidemiologyabout

    Treponema pallidum

    ZHOU Dong-gen*, SUN Da-wei, ZHANG Qi, ZHANGSheng, LU Pei-en, ZHAI Min

    *Ningbo International Travel Health CareCenter, Ningbo, Zhejiang 315012,China

    Abstract:  In recent years, theincidence of syphilis is rising in the developed country, such asEurope and USA, with the high prevalence of syphilis in manydeveloping countries, this has become an important public healthproblem. Advanced molecular epidemiological methods are more andmore applied to the research of syphilis. This article describesthe characteristics of the evolution, variability and time,geographic and population distribution of syphilis to provide atheoretical basis for the prevention and control of bordercrossings with positive and effective manner.

    Key words:   Treponema pallidum;Molecular epidemiology; Distribution; Prevention and control

    《中国国境卫生检疫杂志》