2009年深圳口岸流感疫情监测结果分析

    刘春芳，刘君，叶健忠，辛本强，李东晓，辛刚

    深圳国际旅行卫生保健中心，广东 深圳 518033

    摘要：目的 分析深圳口岸2009年流感监测结果，了解口岸这一特定人群流感流行特征。方法选择监测期内由深圳罗湖口岸、福田口岸、深圳湾口岸3个传染病监测口岸工作部采集入境有流感样症状的发热旅客鼻咽拭子样本，提取病毒RNA，采用实时荧光定量PCR法进行检测；同时进行流行病学个案调查。结果共采集鼻咽拭子样本2166份，其中497例阳性，总阳性率为22.95%。甲型H1N1流感阳性264例（占53.12%），季节性甲型流感阳性220例（占44.27%），季节性乙型流感阳性13例（占2.62%）。男性样本1590份，阳性339例（阳性率21.32%）；女性样本576份，阳性158例（阳性率27.43%）。10～19岁年龄组甲型流感病毒阳性率最高，为21.91%。2009年7、8月流感阳性率最高，阳性率分别为46.70%，41.44%；其次为2009年1、2月，阳性率分别为19.61%、21.70%。结论深圳口岸存在甲型H1N1、季节性甲型和乙型3种流感流行，以甲型H1N1和季节性甲型流感病毒为优势流行毒株；青少年易于感染甲型流感。

    关键词：口岸；流感；监测；流感样症状；荧光定量PCR

    中图分类号：R511.7　文献标识码：B

    Influenza surveillance at Shenzhen ports in2009

    LIU Chun-fang, LIU Jun, YE Jian-zhong, XINBen-qiang, LI Dong-xiao， XIN Gang

    Shenzhen International Travel Health CareCenter, Shenzhen, Guangdong 518033, China

    Abstract:   Objective  To study on influenza surveillance data from entry people, and tounderstand the influenza epidemiological trends at Shenzhenports.   Methods   Nasopharyngeal swabs frompatients with symptoms of influenza-like illness were collectedfrom January 2009 to December 2009 at Shenzhen ports. Influenzavirus was detected by real time PCR.  Results   In total of 2166 swabs, 497 cases werepositive, the rate was 22.95%. Influenza A (H1N1) was thepredominant strain with ratio of 53.12% (264/497) which followed byseasonal A (44.27%, 220/497) and seasonal B (2.62%, 13/497).Influenza A (H1N1) was more prevalent in age group between 10～19.From January 2009 to December 2009, there were two peaks forinfluenza A virus which were in January to February and July toAugust.   Conclusion   Influenza A (H1N1) wasmore predominant than seasonal A in the summer of 2009.

    Key words:   Port; Influenza;Surveillance; Influenza-like illness; Real-time PCR

    《中国国境卫生检疫杂志》