基于症候群监测初步建立我国口岸入境人员传染病监测网络及其2009—2011年监测结果分析

   胡孔新1，平芮巾1，刘胜牙2，师永霞3，莫秋华4，张建明5，张琦6，侯咏7，郭文秀8，朱京京9，

    王汉华10，孙肖红1，马雪征1，杨宇1，杨鹏飞1，张丽萍1，王宝麟1

    1.中国检验检疫科学研究院，北京100123；2.深圳国际旅行卫生保健中心；3.广东检验检疫局检验检疫技术中心；

   4.珠海国际旅行卫生保健中心；5.福建国际旅行卫生保健中心；6.宁波出入境检验检疫局；7.黑龙江出入境检验检疫局；

    8.内蒙古国际旅行卫生保健中心；9.江苏国际旅行卫生保健中心无锡分中心；10.湖北国际旅行卫生保健中心

    摘要：目的了解我国入境人群发热症候群和腹泻症候群的病原谱构成数据，促进我国入境传染病网络实验室监测网络技术平台建立和完善。方法通过口岸体温监测、医学巡查、主动申报、健康体检等手段，于2009年5月—2011年3月间，联合9个直属检验检疫局所属口岸建立监测哨点并对筛选出的入境发热及腹泻人员进行样本采集、统一病原谱检测及数据分析方法。结果9个哨点口岸共采集来自包括5大洲36个国家及地区的1878例样本，其中，阳性样本数为964例，检测出20种阳性病原体，总病原检出率为51.33%。发热伴呼吸道症候群、腹泻症候群和其他症候群阳性检出率进行比较，差异有统计学意义；采集样本中季节性甲型流感病毒、乙型流感病毒和2009甲型H1N1流感各年龄组阳性样本率进行比较，差异有统计学意义，三者的阳性样本25~年龄组最高，60岁以上人群的阳性样本数较低；9个哨点口岸阳性样本检出率进行比较，差异有统计学意义；中国籍和外籍入境人员样本流感病毒与其他病毒检出率进行比较，差异有统计学意义。结论通过统一的传染病样本监测方法，初步建立我国入境口岸传染病监测网络技术平台。

    关键词：入境人员；传染病；监测网络；症候群；分析；哨点口岸

    中图分类号：R183　文献标识码：B

    The initial establishment and analysis on thesurveillance network

    platform of infectious diseases among entrypersonnel at ports

    based on syndrome monitoring during 2009 to2011

    HU Kong-xin*, PING Rui-jin, LIU Sheng-ya, SHIYong-xia, MO Qiu-hua, ZHANG Jian-ming,

    ZHANG Qi, HOU Yong, GOU Wen-xiu, ZHUJing-jing,WANG Han-hua, SUN Xiao-hong,

    MA Xue-zheng, YANG Yu, YANG Peng-fei, ZHANGLi-ping, WANG Bao-lin

    Chinese Academy of Inspection and Quarantine,Beijing 100123,China

    Abstract:   Objective  To obtain the data of pathogen spectrum constitute of the entryinfectious diseases and to establish the surveillance networktechnology platform of the entry Infectious diseases initially inChina.  Methods   The surveillance on infectiousdiseases among fever and diarrhea-like cases at entry ports in2009.5～2011.3 were carried out through temperature screening,health declaration, medical patrol and health examination and thepathogen spectrum were analyzed on the corresponding samples. Results   1878 samples were collected totally whichoriginated from the five continents, 36 countries and regions, Atotal of 20 positive pathogens and 964 samples were foundpositively and the positive rate was 51.33%. The difference of thepositive detection rate of the febrile respiratory syndrome,diarrhea syndrome and the other syndrome was statisticallysignificant; there were significant difference among seasonalinfluenza A virus, influenza B virus and 2009 Influenza A (H1N1) ofthe positive detection rate in all age groups; these positivesamples were the highest in 25 year old group and the lowest beyond60 year old groups; the difference of positive detection rate amongthe nine points of entry was statistically significant; thedifference the detection of influenza A virus and other kinds ofviruses of the chinese and foreign entry staffs was statisticallysignificant.   Conclusion   The networktechnology platform of the surveillance on infectious diseases inchina points of entry have been established initially.

    Key words:   Entry personnel;Infectious diseases; Surveillance network; Syndrome monitoring;Port

    《中国国境卫生检疫杂志》