艾滋病感染窗口期实验诊断技术和方法

    孙 志 云 华 陈宇飞 郭文秀

    （内蒙古国际旅行卫生保健中心，呼和浩特 010020）

    摘要从艾滋病病毒感染到抗体产生之前或没有检测到抗体出现的这个时期称为窗口期，窗口期的存在给艾滋病检测带来了一定的困难，迄今为止，窗口期的检测还是依靠实验室检测，本文就实验室检测的最新方法第四代ELISA检测试剂、p24抗原测定、病毒载量测定以及流式细胞技术等检测技术在窗口期诊断中的应用作简要综述。进一步缩短窗口期的时间，对于口岸艾滋病的预防与控制具有重要的意义。

    关键词 艾滋病；窗口期；诊断；实验室检测

    〔中图分类号〕　R512.91 R446　〔文献标识码〕　B

    Techniques and Methods of LaboratoryDiagnosis on HIV Window Period     Sun zhi, YunHua, Chen Yufei, Guo Wenxiu. Inner Mongolia International TravelHealth Care Center, Huhehaote 010020, China.

    [Abstract]  The “"window period” of HIVinfection is a period when the infected person may not be ill atall and may not test positive, but they will have a high viral loadand be very infectious. The test of HIV in window period has to bedetected by the tests in Lab now. In this paper, four kinds of newlab test methods for the “window period” of HIV infection have beenintroduced briefly, they are the fourth generation ELISA , p24antigen, HIV-1 viral load test and flow cytometry(FCM).It isimportant significance to reduce the test time of window period forthe control and prevention .

    [Key words ]  AIDS； Window period；Diagnosis; Lab test