黑龙江林区出入境人员嗜吞噬细胞无形体血清抗体检测

    黑龙江林区出入境人员嗜吞噬细胞无形体血清抗体检测

    丁大伟1 付维明1 黄玉明1 梁慧杰1 王延禄1 杨春江1 王晓杰2

    （1.黑龙江出入境检验检疫局，哈尔滨 150001;2.黑龙江省皮肤病防治研究所,哈尔滨150001）

    摘要 〔目的〕了解东北林区出入境人员嗜吞噬细胞无形体抗体水平。评估我国东北林区出入境人员嗜吞噬细胞无形体感染的潜在公共卫生危害，为人粒细胞无形体病的防控提供流行病学资料。〔方法〕采用间接免疫荧光检测方法对东北林区出入境体检人群血清嗜吞噬细胞无形体抗体进行检测，并对检测结果进行统计分析。〔结果〕共检测243份血清，其中阳性8份，阳性率为3.29%，1份抗体滴度达到1:320。〔结论〕我国东北林区人群中可能存在嗜吞噬细胞无形体既往感染。

    关键词人粒细胞无形体病；嗜吞噬细胞无形体；间接免疫荧光法；血清；抗体；出入境人员；林区

    〔中图分类号〕　R183.5　〔文献标识码〕　B

    Detection of Anaplasma phagocytophilum amongEntry-exit Personnel in Forest Region of HeilongjiangProvince   Ding Dawei1, Fu Weiming1, Huang Yuming1, LiangHuijie1, Wang Yanlu1, Yang Chunjiang1, Wang Xiaojie2. (1.Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin150001, China. 2. The Instiute of Dermatology of HeilongjiangProvince, Harbin 150001,China)

    [Abstract]   Objective  To evaluate the seroprevalence of humangranulocytic anaplasmosis inNortheastern China, and to provide evidences of prevention andcontrol for human granulocytic anaplasmosis. Method   Among entry-exit personnel, the blood serum wastested by an immunofluorescence assay.  Result   In243 samples, 8 cases were positive, the rate was 3.29%. Meanwhile,it showed antibodies to Anaplasma phagocytophilum at a titre of1∶40， in which, 1 case reached 1∶320. Conclusion  Infectionwith Anaplasma phagocytphilum seems to occur in NortheasternChina.

    [Key words]   Human Anaplasmaphagocytophilum; Indirect immunofluorescence; Blood serum;Antibody; Entry-exit personnel; Forest region