上海出入境人员结核病实验室检测情况分析

    王 健 方 筠 张 琳 章 琪 张晓航 田桢干

    （上海国际旅行卫生保健中心，上海 200335）

    摘要 〔目的〕 了解2008年上海出入境人员结核病的实验室检测情况。〔方法〕对2008年上海口岸出入境人员检疫疾病监测过程中，胸片X射线检测怀疑活动性肺结核的患者进行痰液的抗酸染色检查、分支杆菌培养以及细菌鉴定。〔结果〕2008年1—12月上海地区出入境人员X射线检测怀疑活动性肺结核患者28人。痰涂片抗酸杆菌阳性的共5例（占17.86%），其中1~9条/100视野的3例，1~2条/300视野的2例。痰培养阳性16例，占57.14%；阴性12例，占43.86%；其中液体培养及LJ培养均为阳性9例；液体培养阴性、LJ培养阳性1例；液体培养阳性、LJ培养阴性6例。培养阳性的菌株中鉴定为结核分支杆菌复合群的为4例，占25.00%；鉴定为非结核分支杆菌（NTM）的为12例，占75.00%。经核酸测序显示NTM中，胃、堪萨斯分支杆菌2例，脓肿、龟分支杆菌8例，戈登分支杆菌1例，偶然分支杆菌1例。〔结论〕加强对出入境重点人群的结核病监测具有重要意义，同时实验室需要提高痰涂片的检出率，重视疾液培养技术，努力提高检测能力。

    关键词 结核分支杆菌；痰培养；细菌鉴定；出入境人员；上海口岸

    〔中图分类号〕　R51　〔文献标识码〕　B

    Sputum Screening Results for Tuberculosis ofEntry-Exit Population at Shanghai Port  Wang Jian, Fang Yun,Zhang Lin, Zhang Qi, Zhang Xiaohang, Tian Zhengan. ShanghaiInternational Travel Healthcare Center, Shanghai 200335,China.

    [Abstract]   Objective  To realize the data from the sputum Screening for TB of Entry- ExitPopulation at Shanghai Port in 2008.  Method    Investigation of sputum smear screeningand mycobacterium culture of Entry- Exit Population at Shanghaiport who had been found some suspicion on a chest x-ray in 2008.Result   In 2008, 28 cases have abnormal chest x-rayresult and need further testing at Shanghai Port. In which, 5 caseswere positive result of Z-N stain on sputum smear.15 positive MGITtube cultures and 10 positive LJ cultures were found .There were 4MTB complex, 2 M. gastri or M. kansasii, 7 M. abscessus or M.chelonae,1 M. gordonae and 1 M. fortuitum fort  in sputum culture.  Conclusion  We must strengtheninternational traveler’s blood test screening and surveillance, Itis important to control transmittment of Tuberculosis bytravelers.

    [Key words]   Tuberculosis ; Sputumculture; Identification; Entry-exit population;Shanghai Port